Selected Publications

Huang, H., Ni, K., Li, C., Cai, M., Liu, Y., Zhang, J., Shen, Y., Chen, Y., Sun, J., Shao, J*., Liu, Y*., Ji, W*. and Jiao, J*., 2026. TRIM25 promotes glioblastoma progression by stabilizing HIF-1α expression in normoxia through K11/K29 polyubiquitination. Cell Death & Disease 17, p.530

Guillon, M., Brin, M., Gabet, E., Gromaire, J., Bernard, M., Laurent, L., Rabin, T., Bianchin, L., Veziano, M., Kloda, J., Bernard, A., Asali, L., Liu, Y. and Flamier, A., 2026. MECP2 mutations rewire human ESC fate and bias cortical lineage commitment. Stem Cell Reports 21(5), p.102895.

Eshaghi, B., Wang, E.Y., Mursalova, S., Forster, T.A., Lasrado, N., Tian, J., Artzi, D., Lin, S.Q., Wu, Z., Yang, X., Chung, W.T., Sadeghi, I., Garcia, J., Chen, Z., Sheridan, O., Das, R., Lau, A., Gurram, A., Mainou, B.A., Jones, K.A.V., Liu, Y., Barouch, D.H., von Andrian, U.H., Langer, R. and Jaklenec, A., 2026. Am80-lipid nanoparticles serve as an enteric mucosal adjuvant following parenteral immunization with inactivated polio vaccine. Science Advances 12(23), p.eaea5433.

Wang, E.Y., Calle, E.A., Ying, B., Eshaghi, B., Zhang, L., Yang, X., Lin, S.Q., Han, J., Backx, A.G., Huang, Y., Mursalova, S., Qi, C.J., Liu, Y., Langer, R. and Jaklenec, A., 2026. TIMED: Temporal intervention with microparticle encapsulation and delivery—A programmed release system for post-myocardial infarction therapy. Cell Biomaterials 2(1), p.100249.

Liu, Yi, Troy W. Whitfield, George W. Bell, Ruisi Guo, Anthony Flamier, Richard A. Young, and Rudolf Jaenisch. "Exploring the complexity of MECP2 function in Rett syndrome." Nature Reviews Neuroscience (2025): 1-20.

Liu, Yi, Ruisi Guo, and Rudolf Jaenisch. "Rett Syndrome: Thinking Beyond Brain Borders." Brain-Body Connections: Bidirectional Communication Between the Brain and Body Systems (2025): 243-263.

Liu, Y., Flamier, A., Bell, G.W., Diao, A.J., Whitfield, T.W., Wang, H.C., Wu, Y., Schulte, F., Friesen, M., Guo, R. and Mitalipova, M.,Liu, X.S, Vos, S.M., Young, R.A., and Jaenisch, R.  2024. MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. Neuron, 112(12), pp.1943-1958.

Liu, Y., Kim, J., Philip, R., Sridhar, V., Chandrashekhar, M., Moffat, J., van Breugel, M. and Pelletier, L., 2020. Direct interaction between CEP85 and STIL mediates PLK4-driven directed cell migration. Journal of cell science, 133(8), p.jcs238352.

Liu, Y. and Pelletier, L., 2019. A magic bullet for targeting cancers with supernumerary centrosomes. The EMBO Journal, 38(2), p.e101134.

Liu, Y., Gupta, G.D., Barnabas, D.D., Agircan, F.G., Mehmood, S., Wu, D., Coyaud, E., Johnson, C.M., McLaughlin, S.H., Andreeva, A. Freund, S.M., Robinson, C.V., Cheung, S.W.T., Raught, B., Pelletier, L., and van Breugel, M. 2018. Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nature communications, 9(1), p.1731.

Shao, X.*, Liu, Y.* (co-first), Yu, Q., Ding, Z., Qian, W., Zhang, L., Zhang, J., Jiang, N., Gui, L., Xu, Z. and Hong, Y., Ma, Y., Wei, Y., Liu, X., Jiang, C., Zhu, M., Li, H., Li, H. 2016. Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b. Cell Research, 26(5), pp.593-612.

Gupta, G.D.*, Coyaud, É.*, Gonçalves, J.*, Mojarad, B.A.*, Liu, Y., Wu, Q., Gheiratmand, L., Comartin, D., Tkach, J.M., Cheung, S.W. and Bashkurov, M., Hasegan, M., Knight, J.D., Lin, Z.Y., Schueler, M., Hildebrandt, F., Moffat, J., Gingras, A.C., Raught, B., and Pelletier, L. 2015. A dynamic protein interaction landscape of the human centrosome-cilium interface. Cell, 163(6), pp.1484-1499.